Brain health supplements are gaining popularity as people look to protect their memory from aging, enhance mental energy (to excel at work), and balance mood (so many hormones that influence how we feel are located in the brain.
The thing is: some of these products work, while others hold gimmicky false promises, ineffective ingredients, and insufficient doses. Here’s what you need to know about brain health supplements, the best ingredients to look for, and a list of our expert-vetted picks.
They can if they include science-backed ingredients at clinically relevant doses. No, they won’t magically restore your memories or provide superhuman cognitive abilities, but both human and animal studies that some supplements can help with multiple aspects of memory:1,2
This is your ability to remember certain experiences you’ve had, like what you did to celebrate your birthday last year.
This is your ability to combine multiple senses into the same memory, like how you felt at your last birthday and what your cake smelled like.
This is your ability to remember something while it’s happening, like the name of a new acquaintance in the middle of a conversation with them.
This is your ability to file away memories to long-term storage, like remember that name for years to come.
What to look for
Some supplement ingredients have more research than others. And these six are the ones you want to focus on.
Citicoline is a naturally occurring compound in the brain, and its supplemental form is also beneficial for brain health. This is the ingredient to look for if you want to focus on memory, and it also supports neurotransmitter levels and energy production.*3
This amino acid is a precursor to important neurotransmitters like dopamine and epinephrine. Research shows it can help balance stress, enhance focus, and support working memory.*4
This antioxidant has long been touted for its longevity benefits—including cognitive longevity. It has neuroprotective properties and supports healthy blood flow to the brain (ensuring this vital organ gets the oxygen and nutrients it needs).*5
This nootropic compound helps regulate healthy neurotransmitter levels; bolster memory, learning, and cognition; and protect nerve cells.*7
This nootropic compound helps regulate healthy neurotransmitter levels; bolster memory, learning, and cognition; and protect nerve cells.*7
This herb is traditionally used in Ayurvedic medicine. And research shows it can help with memory retention while promoting overall mental well-being.*6
This nootropic compound helps regulate healthy neurotransmitter levels; bolster memory, learning, and cognition; and protect nerve cells.*7
How we picked
Not for children
Features 3 clinically studied ingredients (Cognizin® citicoline, resveratrol, and kanna)
Promotes cognitive performance, mental clarity, mood balance, and memory*
Formula backed by experts
Allergen info not clearly displayed
Missing vitamin A, thiamin (B1), niacin (B3), pantothenic acid (B5), biotin, vitamins K1 and K2, iodine, potassium, chromium & molybdenum
Personalized needs approach
Potential additions (phytosterols, MSM, omega-3, CoQ10)
7 capsule serving
High price point
Comprehensive formula
Energy, focus, mood-centering support*
Brain-centric vitamins, amino acids, and other bioactives
Glycowithanolide (ashwagandha bioactive) info missing
Features bacopa, huperzine A, and ashwagandha
Supports memory and mood*
Contains soy (food allergen)
Color added (natural caramel color)
Provides phosphatidylserine
Potent active dose
Supports memory, information retention, and neuronal messages*
Proprietary blends (don’t know the quantity of each ingredient)
Includes L-tyrosine, bacopa, and caffeine
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